So I'v played a fair amount of both No More Heroes 1, and Ninja Gaiden Sigma on PC now.
They're both very bare bones with no PC graphics options within the games themselves, but you start them up and they work, and they both play smoothly for me. I don't have anything to complain about.
Only issue is NG Sigma's controls are still bound as if they are PS3 controls, so for my Xbone controller, by default it's LB for block, since that would be L1 on PS3, you have to switch the triggers, and bumpers around in the options before starting a new game.
But yeah It's fucking Ninja Gaiden baby, I kept replaying the chapter 2 Doku boss until I was able to beat him, Laughed the first time trying when I found out he can just impale you for a 1 shot kill to end the chapter.
No Wiimote controls for NMH1 work very well. I was afraid their might have been that thing that I saw from Heroes paradise gameplay where you need to Click the thumbstick before a finishing blow direction, but no it's just a simple flick.
Controls are X for Low Swing, Y for High Swing, A for Low Melee, B for High Melee. LT lock on, LB for Battery charge, Right stick is most waggle stuff, clashes are super easy with rotating the stick.